Abstract: Under the background of mobile Internet, tourists demand and marketing methods change continuously. The traditional marketing methods of government and related enterprises at tourism destination are facing great challenges. As a popular software, Tik Tok brings new opportunities to tourism destination marketing. This paper applies the grounded theory to analyze and code the interview content of the Tik Tok users, and explores the application path of Tik Tok in tourism destination marketing. The results show that Tik Tok will become the inevitable trend of marketing, because its characteristics are interrelated and cooperated, forming a closed loop of stimulation, arousal, reaction, proximal goal and ultimate goal. The paper also explains Tik Tok with the model architecture diagram. Finally, the paper makes some proposals for tourism destination governments and related enterprises to make reasonable and effective use of Tik Tok for tourism marketing.