Abstract: In this paper, taking Jinping I hydropower station left bank slope as an example, we set up a simplified three-dimensional geological model with weak structural plane. Based on the RFPA^3D centrifugal loading method and the strength reduction method, the progressive failure process of the slope was simulated, and the applicability of different RFPA^3D loading methods in slope stability analysis was discussed by reproducing the progressive failure process of the slope. The simulation results show that compared with the finite element numerical calculation methods such as FLAC^3D and discrete element, the progressive slope failure process simulated by RFPA^3D is simpler, more intuitive and efficient. The analysis of the progressive failure process shows that under natural conditions, the lamprophyre X and faults of the F5, F8, and F2 are the key factors for controlling the overall failure mode of slopes, which should be paid special attention during slope excavation. Stability analysis shows that the safety factor of slope calculated by Centrifuge method is 1.75, which is better than that calculated by SRM method. And the slope failure mode simulated by Centrifuge method is consistent with the actual engineering investigation results. Therefore, the RFPA-Centrifuge method is recommended when analyzing the slope failure mode.