Abstract: A method was established to set up evaluation standard for honey-fried tussilago farfara. The qualitative identification of honey-fried tussilago farfara was performed with thin layer chromatography. Quantitative analysis of tussilagone in honey-fried tussilago farfara was carried out based on high performance liquid chromatography. The chromatographic conditions were octadecylsilane-bonded silica gel as the filler and methanol-water (85:15) as the mobile phase. The detection wavelength was 220 nm. In addition, moisture content and alcohol-soluble extracts were measured with reference to the 2015 Chinese Pharmacopoeia. The experiment results show that the samples have the same color spots with control article and reference crude herb in corresponding chromatography location. The honey-fried tussilago farfara moisture content is less than 14%, and total ashes content must not more than 14%, and the extract not less than 19.0%, and the content of tussilagone not less than 0.12%. It can be concluded that the method is simple, reproducible and stable.