Abstract: At present, rail transit has become one of the main ways for people to travel. However, in its operating environment, electromagnetic interference is generated by a variety of the electrical equipment of the train, and wireless electromagnetic interference sources. Solving the electromagnetic compatibility (EMC) problem of rail transit in the complex electromagnetic environment is key to ensure their safety. To solve this problem, the ability of anti-electromagnetic interference of rail transit was studied in this paper. First, electromagnetic interference problem and its solutions were presented. Second, from the aspects of grounding, filtering, shielding, wiring, and the choice of electronic components, the anti-electromagnetic interference methods were proposed. And based on these principles, from two dimensions of the vehicle and equipment level, the detailed anti-electromagnetic interference design methods of rail transit were proposed for specific equipment, components and entire vehicles. Finally, taking Wenzhou City Line S1 Project as examples, the rationality and effectiveness of the proposed anti-electromagnetic interference design methods were verified through the field test.