Abstract: Aiming at the shortcomings of the wired networking of the fire monitor control system in ancient buildings, wharves, scenic spots and other places, such as complicated installation and wiring, and difficulty in later maintenance, a fire monitor control system based on the NB-IoT and IoT cloud platform is designed. The STM32 microcontroller is used as the system’s main controller, and the NB-IoT module based on the M5310A chip is used as the wireless transmission module, and the NB-IoT wireless transmission technology and the OneNET cloud platform are used to realize the networking of the fire monitor control system, and through the client terminal, the fire alarm situation and the status information of the fire monitor can be checked at any time, and the fire monitor can also be controlled remotely. The test results show that the system has good stability, and the wireless networking based on the NB-IoT can simplify the system’s networking and reduce the power consumption of the system. It provides a reference for the design of the fire monitor control system .