Abstract: To explore the relationship of academic self-efficacy, procrastination and burnout, a total of 391 middle school students in Guizhou province were investigated with three questionnaires: Academic Self-Efficacy Inventory, Academic Procrastination Inventory and the Adolescent Student Burnout Inventory. The results indicate that: the academic self-efficacy is negatively correlated with academic procrastination and academic burnout; the academic self-efficacy may, to a large degree, give counterclockwise prediction to academic procrastination and academic burnout; Exhaustion, learning cynicism and academic burnout play a partial intermediate role between academic self-efficacy and procrastination.