Since the reform and the opening up, China’s economy and society have developed rapidly. At the same time, divorce rate has been rising, especially since 2002, and the accelerated divorce rate has surpassed many developed countries. Based on the provincial panel data (excluding Hong Kong, Macao and Taiwan) from 2010 to 2018 in China, this paper uses the fixed effect model to analyze the influencing factors of divorce rate. The results show that the logarithm of per capita GDP, the proportion of urban population, the rate of urban unemployment, the sex ratio of the population aged 15 and above, and the logarithm of housing price all have positive and significant impacts on divorce rate, in which the increase of per capita GDP and housing price have greater correlation with the continuous rise in divorce rates in recent years. To reduce the divorce rate, the following countermeasures should be taken: cultivating healthy marriage and childbearing concept, paying attention to humanized urban construction, appropriatly controling housing prices, strengthening employment service guarantee for young couples, and perfecting the marriage law.