Abstract: The Book of Changes is known as the head of Classics, and the source of Taoism. The history of the occurrence and development of The Book of Changes is a history of the spiritual growth of the Chinese nation. The Book of Changes contains rich national wisdom, such as self-improvement and moral integrity, knowing one’s ability and advancing with the time, being aware of difficulties and moral cultivation, being honest and building an atmosphere of fair and harmony, being flexible when facing changes and seeking common ground while reserving differences, fallowing the natural laws, respecting justice and living peaceful life, etc. The paper argues that these wisdom are the spiritual power and source of strength for Chinese people to realize the great rejuvenation of the nation today. It is worth for all Chinese people remembering and practicing.