Abstract: In lexicalization study, researchers generally focused on the semantic specificity and historical development of a word combination. From different perspective, the paper is to investigate the generality of semantic categories and their synchronic results. Through the investigation of the "Nouns+Orientation" structure in Lexicon of Common Words in Contemporary Chinese, the paper holds the view that there are some rules of semantic categories in lexicalization of the combinations. By analyzing the features of directional dimension, irregular orientation, the semantics of nouns and the difference of lexicalization degree of the combinations, the paper, based on the target semantic category and the degree of lexicalization classification, is to prove the naturalness and demand are the factors that have influenced on the lexicalization of "Nouns+Orientation" combinations and the form of the two kinds of rules are both restricted by the cognitive factors.